Dysfunctional cerebrovascular tone contributes to cognitive impairment in a non-obese rat model of prediabetic challenge: role of suppression of autophagy and modulation by … W Fakih, A Mroueh, H Salah, AH Eid, M Obeid, F Kobeissy, H Darwish, ... Biochemical Pharmacology 178, 114041, 2020 | 35 | 2020 |
Western diet aggravates neuronal insult in post-traumatic brain injury: Proposed pathways for interplay A Shaito, H Hasan, KJ Habashy, W Fakih, S Abdelhady, F Ahmad, ... EBioMedicine 57, 2020 | 30 | 2020 |
Early metabolic impairment as a contributor to neurodegenerative disease: Mechanisms and potential pharmacological intervention W Fakih, R Zeitoun, I AlZaim, AH Eid, F Kobeissy, KS Abd‐Elrahman, ... Obesity 30 (5), 982-993, 2022 | 18 | 2022 |
COVID-19 promotes endothelial dysfunction and thrombogenicity: role of proinflammatory cytokines/SGLT2 prooxidant pathway A Mroueh, W Fakih, A Carmona, A Trimaille, K Matsushita, B Marchandot, ... Journal of Thrombosis and Haemostasis 22 (1), 286-299, 2024 | 6 | 2024 |
Healthy meal, happy brain: How diet affects brain functioning F Ahmad, H Hasan, S Abdelhady, W Fakih, N Osman, A Shaito, ... Front Young Minds [Internet] 9, 1-9, 2021 | 3 | 2021 |
Activated factor X stimulates atrial endothelial cells and tissues to promote remodeling responses through AT1R/NADPH oxidases/SGLT1/2 W Fakih, A Mroueh, DS Gong, S Kikuchi, MP Pieper, M Kindo, ... Cardiovascular Research, cvae101, 2024 | | 2024 |
Empagliflozin treatment prevented oxidative stress, macrophage infiltration, pro-inflammatory and pro-fibrotic responses in the left ventricle of isoprenaline-induced Takotsubo … T Tatarcheh, S Amissi, K Matsushita, A Mroueh, A Trimaille, DS Gong, ... European Heart Journal 44 (Supplement_2), ehad655. 3125, 2023 | | 2023 |
Increased pro-remodeling and pro-thrombotic responses in the left compared to the right atrial appendage: role of low-grade inflammation and the AT1R/NADPH oxidases/SGLT2 pro … W Fakih, A Mroueh, C Alhelou, M Kindo, A Mommerot, JP Mazzucotelli, ... European Heart Journal 44 (Supplement_2), ehad655. 3123, 2023 | | 2023 |
SGLT2 expression in the left ventricle of cardiac patients is correlated with low-grade inflammation involving the pro-oxidant AT1R/NADPH oxidases/SGLT2 crosstalk: potential … A Mroueh, W Fakih, DS Gong, C Auger, MP Pieper, O Morel, ... European Heart Journal 44 (Supplement_2), ehad655. 3150, 2023 | | 2023 |
Importance de la voie pro-oxydante AT1R/NADPH oxydase/SGLT1/2 dans les réponses pro-sénescentes, pro-inflammatoires et pro-fibrotiques des cellules endothéliales auriculaires … W Fakih Strasbourg, 2022 | | 2022 |
SGLT2 Expression in the Coronary Microvessel Endothelium and Cardiomyocytes of Cardiac Patients: Determinant Role of Low-Grade Inflammation and Induction of Endothelial Dysfunction A Mroueh, W Fakih, DS Gong, C Auger, K Matsushita, O Morel, ... Circulation 146 (Suppl_1), A11270-A11270, 2022 | | 2022 |
Upregulation of SGLT1 and 2 promotes oxidative stress in right atrial appendages of patients with low-grade inflammatory responses: potential role in atrial fibrillation W Fakih, A Mroueh, C Auger, MP Kindo, A Mommerot, JP Mazzucotelli, ... European Heart Journal 43 (Supplement_2), ehac544. 2925, 2022 | | 2022 |
SGLT1/2 expression in the heart of transplanted patients is associated with inflammatory induction of oxidative stress: potential protective effect of SGLT2 inhibitors DS Gong, A Mroueh, K Matsushita, W Fakih, C Auger, MH Oak, MP Pieper, ... European Heart Journal 43 (Supplement_2), ehac544. 3007, 2022 | | 2022 |
FXa promotes endothelial dysfunction and pro-remodeling responses in atrial endothelial cells involving PAR1 and 2 and AT1R/NADPH oxidase/SGLT1/2 pro-oxidant pathways W Fakih, A Mroueh, D Gong, P Ohlmann, O Morel, VS Kerth, L Jesel EUROPEAN JOURNAL OF HEART FAILURE 24, 280-280, 2022 | | 2022 |
Pro-Inflammatory Cytokines-Induced SGLT1/2 Expression Promotes Endothelial Dysfunction A Mroueh, SH Park, W Fakih, S Amissi, DS Gong, K Matsushita, C Auger, ... JOURNAL OF CARDIOVASCULAR PHARMACOLOGY 78, 94-95, 2021 | | 2021 |
Protective effects of dapagliflozin on vascular remodeling in the carotid artery following balloon injury–potential role of angiotensin and purinergic signaling K Matsushita, C Sato, C Bruckert, D Gong, S Hmadeh, W Fakih, L Remila, ... European Heart Journal 42 (Supplement_1), ehab724. 3409, 2021 | | 2021 |
Thrombin and factor Xa promote premature senescence and remodeling in areas at risk of the left appendage and in atrial endothelial cells: potential modulation by SGLT1 and/or … W Fakih, H Hasan, D Gong, P Ohlmann, O Morel, V Schini Kerth, L Jesel, ... European Heart Journal 42 (Supplement_1), ehab724. 3269, 2021 | | 2021 |
Western diet aggravates neuronal insult in post-traumatic brain injury: Proposed pathways for interplay S Abdullah, H Hasan, KJ Habashy, W Fakih, S Abdelhady, F Ahmad, ... Elsevier, 2020 | | 2020 |
Metabolic Stress Leads to Neuro‐inflammation and Mild Cognitive Impairment Prior to Development of Hyperglycemia: Role of Autophagy Suppression WK Fakih, AK Mroueh, HF Salah, MF Obeid, FF Kobeissy, H Darwish, ... The FASEB Journal 33 (S1), 501.13-501.13, 2019 | | 2019 |